Antibiotic action of pyocyanin
نویسندگان
چکیده
منابع مشابه
The complexities of antibiotic action
Antibiotics are arguably the most successful medicine on the planet, but the one under huge threat from antibiotic resistance in the face of diminishing new antimicrobial discovery efforts (Hancock, 2007). One of the great hopes for discovering new antibiotics arose when whole-genome sequencing came of age in 1995 with the decoding of the Haemophilus influenzae genome, followed rapidly by those...
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Antibiotic U-24,544, a new antibacterial agent, was found to be an effective uncoupler of phosphorylation associated with the oxidation of glutamate and succinate in rat liver mitochondria. Respiration was inhibited during glutamate oxidation but not during succinate oxidation. In a medium deficient in inorganic phosphate, the agent showed slight stimulation of mitochondrial glutamate oxidation...
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The fruits of Solanum incanum Linnaeus are extensively used in Kenya for the treatment of cutaneous mycotic infections and other pathological conditions. The therapeutic activity of the berries has been attributed to their content of solanine and related glycoalkaloids, which are saponins and cytostatic poisons. In the present study, however, a simpler more potent antimicrobial substance with a...
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Aminoglycoside antibiotics that bind to the ribosomal A site cause misreading of the genetic code and inhibit translocation. The clinically important aminoglycoside, gentamicin C, is a mixture of three components. Binding of each gentamicin component to the ribosome and to a model RNA oligonucleotide was studied biochemically and the structure of the RNA complexed to gentamicin C1a was solved u...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1981
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.20.6.814